Growth in ataxia telangiectasia

Abstract Background Ataxia telangiectasia (A-T) is a DNA repair disorder that affects multiple body systems. Neurological problems and immunodeficiency are two important features of this disease. At time, main severity groups defined in A-T: classic (the more severe form) mild. Poor growth common problem A-T. An objective study was to develop references for Another compare patterns A-T mild with each other the general population, using CDC references. A final examine effects chronic infection on height. Results We found patients were smaller overall, suffered from height weight faltering continued throughout childhood adolescence. When compared references, median heights weights both male female eventually fell or below 3rd centile charts. Height pronounced females. Birthweight lower group whereas birth length not. Finally, we investigated BMI relation number infections no association. Conclusions Classic appears affect utero. Although children appear grow well very early life, begins early, unrelenting.